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Invitrogen™ Factor VII Monoclonal Antibody (5031)
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Product Code. 11599852
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Quantity:
100 μg
Unit Size:
100µg
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11599852 100 μg 100µg
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Product Code. 11599852 Supplier Invitrogen™ Supplier No. MA143011

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Description

Mouse Monoclonal Antibody

MA1-43011 detects Factor VII in human samples. MA1-43011 has successfully been used in radioimmunassays, western blot and ELISA applications. MA1-43011 was derived from human factor VII, factor VIIa and BFPRck factor VIIa.

Coagulation factor VII is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in F7 production can cause coagulopathy.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Factor VII
Applications ELISA, Radioimmune Assays (RIA), Western Blot
Classification Monoclonal
Clone 5031
Concentration 14.1 mg/mL
Conjugate Unconjugated
Formulation 50% water with 50% glycerol and no preservative
Gene F7
Gene Accession No. P08709
Gene Alias AI132620; Cf7; Coagulation factor VII; coagulation factor VII (serum prothrombin conversion accelerator); eptacog alfa; F7; Factor 7; Factor VII heavy chain; Factor VII light chain; Factor7; FVII; FVII coagulation protein; proconvertin; Serum prothrombin conversion accelerator; SPCA
Gene Symbols F7
Host Species Mouse
Immunogen Human factor VII/VIIa.
Purification Method SDS-PAGE
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2155
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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