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Invitrogen™ FARSA Polyclonal Antibody

Description
Recommended positive controls: 293T, H1299, HeLa, HepG2, Molt-4, Raji. Predicted reactivity: Mouse (93%), Rat (94%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (95%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS2 is a phenylalanine-tRNA synthetase (PheRS) localized to the mitochondrion which consists of a single polypeptide chain, unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and in the eukaryotic cytoplasm. Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. FARS1 encodes a mitochondrially-located phenylalanine-tRNA synthetase (PheRS) which consists of a single polypeptide chain unlike the (alpha-beta)2 structure of the prokaryotic and eukaryotic cytoplasmic forms of PheRS. Structure analysis and catalytic properties indicate mitochondrial PheRSs may constitute a class of PheRS distinct from the enzymes found in prokaryotes and the eukaryotic cytoplasm.
Specifications
Specifications
| Antigen | FARSA |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.39 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7 |
| Gene | FARSA |
| Gene Accession No. | Q8C0C7, Q9Y285 |
| Gene Alias | 0610012A19Rik; CML33; FARS; Farsa; FARSL; FARSLA; FRSA; PheHA; phenylalanine tRNA ligase 1, alpha, cytoplasmic; phenylalanine--tRNA ligase alpha chain; phenylalanine--tRNA ligase alpha subunit; phenylalanine-tRNA synthetase alpha-subunit; phenylalanine-tRNA synthetase-like, alpha subunit; phenylalanyl-tRNA synthetase alpha chain; phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase, alpha subunit; phenylalanyl-tRNA synthetase-like, alpha subunit; pheRS |
| Gene Symbols | FARSA |
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