FceR1 alpha Armenian Hamster anti-Mouse, PE, Clone: MAR-1, eBioscience™
Armenian Hamster Monoclonal Antibody
Merk: Affymetrix eBioscience 12-5898-81
Overige gegevens : Gewicht : 0.25000kg
BeschrijvingFceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE. Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one ß and two additional subunits. The latter two are required for signal transduction activity. The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response. When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released. The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma. The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.
|PBS with 0.1% gelatin and 0.09% sodium azide; pH 7.2|
|RP11-550P17.3, FCE1A, FcERI|
|4° C, store in dark, DO NOT FREEZE!|
For Research Use Only.