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Invitrogen™ FDPS Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA528228
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Description
Recommended positive controls: A549, H1299, HCT116, Mouse brain, rat liver. Predicted reactivity: Mouse (89%), Rat (89%), Pig (89%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The isoprene biosynthetic pathway supply the cell with cholesterol, ubiquinone, and various nonsterol metabolites. The farnesylpyrophosphate synthetase enzyme catalyzes the formation of geranyl and farnesylpyrophosphate from isopentenylpyrophosphate and dimethylallyl pyrophosphate. Analysis of FDPS activity and protein in rat liver, accompanied by immunofluorescence and immunoelectron microscopy studies, demonstrated that FDPS is predominantly localized in peroxisomes. 1 Liver tissue from patients with the peroxisomal deficiency diseases Zellweger syndrome and neonatal adrenoleukodystrophy exhibit diminished activities of FDPS and subsequent isoprenoid synthesis.
Specifications
| FDPS | |
| Polyclonal | |
| Unconjugated | |
| FDPS | |
| (2E,6E)-farnesyl diphosphate synthase; 6030492I17Rik; Ac2-125; AI256750; cholesterol-regulated 39 kDa protein; CR 39; dimethylallyltranstransferase; Farnesyl diphosphate synthase; farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase); farnesyl diphosphate synthetase; farnesyl pyrophosphate synthase; farnesyl pyrophosphate synthetase; farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase; Fdps; Fdpsl1; FPP synthase; FPP synthetase; FPPS; FPS; geranyltranstransferase; KIAA1293; mKIAA1293; POROK9; testis-specific farnesyl pyrophosphate synthetase | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 110196, 2224, 83791 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1.35 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| P05369, P14324, Q920E5 | |
| FDPS | |
| Recombinant protein encompassing a sequence within the center region of human FDPS. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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