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Invitrogen™ Fe65 Recombinant Rabbit Monoclonal Antibody (23GB3665), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA553448
This item is not returnable.
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Description
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein, transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene but some of their full length sequence is not known.
Specifications
| Fe65 | |
| Recombinant Monoclonal | |
| Unconjugated | |
| APBB1 | |
| adaptor protein FE65a2; amyloid beta (A4) precursor protein-binding, family B, member 1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); amyloid beta A4 precursor protein-binding family B member 1; amyloid beta precursor protein binding family B member 1; Amyloid-beta A4 precursor protein-binding family B member 1; APBB1; FE65; MGC:9072; Protein Fe65; RIR; stat-like protein | |
| Rabbit | |
| Affinity chromatography | |
| RUO | |
| 322 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot, Immunocytochemistry | |
| 23GB3665 | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| O00213 | |
| APBB1 | |
| A synthetic peptide of human FE65 (650-710AA). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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