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Invitrogen™ FECH Polyclonal Antibody

Description
Recommended positive controls: HeLa, HepG2. Predicted reactivity: Mouse (92%), Rat (93%), Xenopus laevis (87%), Pig (89%), Chicken (85%), Chimpanzee (100%), Bovine (91%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.
Specifications
Specifications
| Antigen | FECH |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.74 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7 |
| Gene | FECH |
| Gene Accession No. | P22830 |
| Gene Alias | AI894116; EPP; FCE; fch; Fcl; FECH; ferrochelatase; ferrochelatase, mitochondrial; Heme synthase; heme synthetase; protoheme ferro-lyase; protoporphyria |
| Gene Symbols | FECH |
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