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Invitrogen™ FEM1A Polyclonal Antibody

Goat Polyclonal Antibody
Brand: Invitrogen™ PA124858
Description
Recommended positive controls: The peptide used to generate this antibody is available for purchase (GTX10911-PEP).. PA1-24858 is expected to cross react with mouse Fem1C (100% conserved) due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
FEM1A (FEM-1 homolog a), also known as EPRAP (Prostaglandin E receptor 4-associated protein), is a 669 amino acid cytoplasmic protein that belongs to the FEM-1 family. FEM1A is present in atheromata and in macrophages derived from peripheral blood monocytes. FEM1A may be a component of an E3 ubiquitin-protein ligase complex and functions as a substrate recognition subunit. It is suggested that FEM1A participates in anti-inflammatory signaling of macrophages via its interaction with EP4. FEM1A is down-regulated in Rhabdomyosarcoma, the most common soft tissue neoplasm of children. FEM1A is considered a candidate gene for polycystic ovary syndrome.
Specifications
| FEM1A | |
| Polyclonal | |
| Unconjugated | |
| FEM1A | |
| AW611390; DKFZp762M136; EPRAP; fem-1 homolog A; fem-1 homolog a (C. elegans); Fem1a; Fem1aa; FEM1a-A; FEM1-alpha; FEM1-alpha-A; feminization 1 homolog a; feminization 1 homolog a (C. elegans); prostaglandin E receptor 4-associated protein; Protein fem-1 homolog A; protein fem-1 homolog A-A; similar to fem-1 homolog a (C.elegans) | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| 14154, 316131 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| Q4V890, Q9Z2G1 | |
| FEM1A | |
| Peptide with sequence C-HIPEKLETFVSLHR, from the C Terminus. | |
| 100 μg | |
| Primary | |
| Mouse, Rat | |
| Antibody | |
| IgG |
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