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Invitrogen™ Human FGFR4, His Tag Recombinant Protein

Product Code. 15428403
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Quantity:
1 mg
100 μg
Unit Size:
100µg
1mg
This item is not returnable. View return policy

Product Code. 15428403

Brand: Invitrogen™ PR4380C

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This item is not returnable. View return policy

Recombinant Protein

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic

FGFR4 is a member of the FGFR family of receptor tyrosine kinases. This family is known to regulate a host of cellular functions including angiogenesis, mitogenesis, osteogenesis, myogenesis, carcinogenesis, cellular differentiation, and tissue repair after injury. The FGFR family has also been implicated in a number of diseases including cancer, rheumatoid arthritis, and diabetic retinopathy. FGFR4 is required for normal down-regulation of the expression of CYP7A1, the rate-limiting enzyme in bile acid synthesis, in response to FGF19. FGFR4 plays a role in postnatal lung development and may be involved in the development of skeletal muscle cell lineages.
TRUSTED_SUSTAINABILITY

Specifications

Accession Number P22455
Concentration See Label
For Use With (Application) Kinase Assay
Formulation 50 mM tris with 0.01% NP-40, 0.01 mM EDTA, 100 mM NaCl, 1 mM DTT, 20% glycerol and no preservative; pH 7.5
Gene ID (Entrez) 2264
Molecular Weight (g/mol) 42.6 kDa
Name Human FGFR4, His Tag
Quantity 100 μg
Regulatory Status RUO - research use only
Gene Alias CD334; CTLA-2-beta protein; FGF Receptor; FGF Receptor 4; FGFR; Fgfr4; FGFR-4; Fibroblast growth factor receptor 4; fibroblast growth factor receptor 4 16 minus form; hydroxyaryl-protein kinase; JTK2; MGC20292; Mpk-11; protein-tyrosine kinase; protein-tyrosine kinase receptor MPK-11; TKF; tyrosine kinase related to fibroblast growth factor receptor; tyrosylprotein kinase
Common Name FGFR4
KinaseFamily FGF Receptor Kinase Family
Protein Length 781-1338
Conjugate Unconjugated
Species Human
Recombinant Recombinant
Protein Tag His-tag
Content And Storage -80°C, Avoid Freeze/Thaw Cycles
Expression System Insect cells
Form Liquid
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