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Description
Antibody detects endogenous levels of total Fgl2.
Fibrinogen-like protein 2 (Fgl2), also known as fibroleukin, is secreted by T cells and is involved in diseases in which thrombosis plays a pivotal role, such as virus-induced fulminant hepatitis, fetal loss syndrome and xenograft rejection. Constitutively expressed in cytotoxic T cells, Fgl2 exerts immunosuppressive effects on both T cell proliferation and dendritic cell maturation. Fgl2 is a serine protease and directly cleaves prothrombin to thrombin. Fgl2 functions in the pathogenesis of diseases including viral-induced hepatitis and Th1 cytokine-induced fetal loss syndrome.
Specifications
Specifications
| Antigen | FGL2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide |
| Gene | FGL2 |
| Gene Accession No. | Q14314 |
| Gene Alias | AI385601; associated with MHV-3 induced prothrombinase activity; cytotoxic T-lymphocyte-specific protein; Fgl2; Fiblp; fibrinogen like 2; fibrinogen-like 2; fibrinogen-like protein 2; Fibroleukin; musfiblp; Prothrombinase; pT49; similar to Fibroleukin precursor (Fibrinogen-like protein 2) (pT49); T49 |
| Gene Symbols | FGL2 |
| Show More |
Product Title
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