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Invitrogen™ FGR Polyclonal Antibody

Goat Polyclonal Antibody
Brand: Invitrogen™ PA517976
This item is not returnable.
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Description
This antibody is predicted to react with canine, human and rat based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 128,000.
FGR is a SRC-related kinase present in hematopoietic cells. FGR signals within multiple pathways including within the integrin pathway and downstream of chemokine and cytokine receptors. This protein contains N-terminal sites for myristylation and palmitoylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. It localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this protein.
Specifications
| FGR | |
| Polyclonal | |
| Unconjugated | |
| FGR | |
| c-fgr; c-fgr protooncogene; c-src2; c-src-2 proto-oncogene; EC 2.7.10.2; feline Gardner-Rasheed sarcoma viral oncogene; feline Gardner-Rasheed sarcoma viral oncogene homolog; FGR; FGR protein; FGR proto-oncogene, Src family tyrosine kinase; FLJ43153; Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; MGC75096; OTTHUMP00000003603; OTTHUMP00000003604; p55c-fgr; p55-c-fgr protein; p55-Fgr; p58c-Fgr; p58-Fgr; proto-oncogene c-Fgr; proto-oncogene tyrosine-protein kinase FGR; SRC2; Tyrosine-protein kinase Fgr; v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog | |
| Goat | |
| Ammonium Sulfate Precipitation | |
| RUO | |
| 2268 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3 | |
| P09769 | |
| FGR | |
| Synthetic peptide sequence (TSAEPQYQPGDQT) corresponding to the C-terminus amino acids of FGR (aa 517-529). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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