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Invitrogen™ Fibrillin 1 Polyclonal Antibody
Description
Immunogen sequence: HCVSGMGMGR GNPEPPVSGE MDDNSLSPEA CYECKINGYP KRGRKRRSTN ETDASNIEDQ SETEANVSLA SWDVEKTAIF AFNISHVSNK VRILELLPAL TTLTNHNRYL IESGNEDGFF KINQKEGISY LHFTKKKPVA GTYSLQISS Highest antigen sequence indentity to the following orthologs: Mouse - 92%, Rat - 91%.
Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with mosaic composition of different types of extracellular modules. Most of the fibrillin molecule is contributed by 47 epidermal growth factor-like (EGF-like) repeats; 43 of them have a consensus sequence for calcium binding (cb). Other modules including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three) are interspersed throughout the molecule[3-7]. Fibrillin 1 contains a proline-rich region close to the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout the connective tissue as integral components of extended fibrils.
Specifications
Specifications
| Antigen | Fibrillin 1 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | FBN1 |
| Gene Accession No. | P35555 |
| Gene Alias | ACMICD; AI536462; Asprosin; B430209H23; ECTOL1; FBN; Fbn1; Fbn-1; Fib-1; fibrillin 1; fibrillin 15; fibrillin-1; GPHYSD2; MASS; MFLS; MFS1; MP340; OCTD; putative; SGS; SSKS; tight skin; Tsk; WMS; WMS2 |
| Gene Symbols | FBN1 |
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