Invitrogen™ Fibroblasts Monoclonal Antibody (D7-FIB), PE

Description

This antibody does not react with mouse or rat. Reconstitute with 1 mL of distilled water. After reconstitution, store product undiluted at 4°C in the dark. For FACS analysis, use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Mouse anti Human Fibroblasts/Epithelial Cells antibody, clone D7-FIB recognizes a approximately 112kDa molecule expressed on the cell surface of human fibroblasts.

Fibroblasts are the least specialized cells in the connective-tissue family. Thay are dispersed in connective tissue throughout the body, where they secrete a nonrigid extracellular matrix that is rich in type I and/or type III collagen. The activation of fibroblasts by inflammatory stimuli results in their migration, proliferation and deposition of extracellular matrix components, important features involved in both wound healing and fibrosis.