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Invitrogen™ Ficolin 3 Monoclonal Antibody (296134)

Description
In direct ELISAs and Western blots, no cross-reactivity with recombinant human Ficolin-2 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.
H-Ficolin (Hakata antigen, Ficolin-3) is an innate immunity pattern recognition molecule found in human serum. H-Ficolin binds to distinct pathogen-associated molecular patterns (PAMP) formed by carbohydrates (GlcNAc, GalNAc and fucose) activating complement through the lectin pathway by means of the associated MASPs ((MBL)-associated serine proteases). H-Ficolin consists of 35 kDa protein chains associated in triplet subunits which are again associated in high molecular weight oligomers by means of disulfide bonds at the N-terminal region.
Specifications
Specifications
| Antigen | Ficolin 3 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | 296134 |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 5% trehalose and No Preservative |
| Gene | FCN3 |
| Gene Accession No. | O75636 |
| Gene Alias | Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; FCN3; FCNH; ficolin (collagen/fibrinogen domain containing) 3 (Hakata antigen); ficolin 3; ficolin-3; HAKA1; Hakata antigen; LOW QUALITY PROTEIN: ficolin-3; MGC22543 |
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