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Invitrogen™ FIGNL1 Polyclonal Antibody

Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA563140
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Description
Immunogen sequence: RLYIPLPEAS ARKQIVINLM SKEQCCLSEE EIEQIVQQSD AFSGADMTQL CREASLGPIR SLQTADIATI TPDQVRPIAY IDFENAFRTV RPSVSPK Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 91%.
The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
Specifications
| FIGNL1 | |
| Polyclonal | |
| Unconjugated | |
| FIGNL1 | |
| fidgetin like 1; fidgetin-like 1; fidgetin-like protein 1; FIGNL1; S30 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 63979 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin) | |
| 0.6 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q6PIW4 | |
| FIGNL1 | |
| Recombinant protein corresponding to Human FIGNL1. Recombinant protein control fragment (Product #RP-92719). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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