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Invitrogen™ Filamin A alpha-2 Polyclonal Antibody
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Product Code. 13463777
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Quantity:
100 μL
Unit Size:
100µL
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13463777 100 μL 100µL
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Product Code. 13463777 Supplier Invitrogen™ Supplier No. PA529598

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Rabbit Polyclonal Antibody

Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji, mouse kidney, PC-12, Rat2. Predicted reactivity: Mouse (98%), Rat (98%), Rabbit (98%), Bovine (99%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
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Specifications

Antigen Filamin A alpha-2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.42 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene FLNA
Gene Accession No. P21333, Q8BTM8
Gene Alias ABP-280; ABPX; actin binding protein 280; actin-binding protein 280; alpha filamin; alpha-filamin; CSBS; CVD1; dilated pupils 2; Dilp2; Endothelial actin-binding protein; Endothelial actin-binding protein 280); F730004A14Rik; filamin A; filamin A, alpha; filamin, alpha; filamin-1; Filamin-A; FLN; FLN1; FLNA; FLN-A; FMD; GENA 379; MNS; NHBP; Non-muscle filamin; OPD; OPD1; OPD2; RGD1560614; XLVD; XMVD
Gene Symbols FLNA
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the C-terminus region of human Filamin A. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 192176, 2316, 293860
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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