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Invitrogen™ Filensin Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA559279
This item is not returnable.
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Description
Immunogen sequence: SAHECHDDEI QLYNEQIETL RKEIEETERV LEKSSYDCRQ LAVAQQTLKN ELDRYHRIIE IEGNRLTSAF IETPIPLFTQ SHGVSLSTGS GGKD Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 82%.
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (also known as phakinin) and the protein product of this gene, filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been found for this gene.
Specifications
| Filensin | |
| Polyclonal | |
| Unconjugated | |
| BFSP1 | |
| Beaded filament structural protein 1; beaded filament structural protein 1, filensin; BFSP1; CP115; CP94; CTRCT33; cytoskeletal protein, 115 KD; filensin; Lens fiber cell beaded-filament structural protein CP 115; lens intermediate filament-like heavy; LIFL-H; LOW QUALITY PROTEIN: filensin; RP4-531H16.2 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 631 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Immunohistochemistry (Paraffin), Immunocytochemistry | |
| 0.2 mg/mL | |
| PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 | |
| Q12934 | |
| BFSP1 | |
| Recombinant protein corresponding to Human Filensin. Recombinant protein control fragment (Product #RP-99408). | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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