missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. 11514783

Invitrogen™ FK506 Monoclonal Antibody (FK1)
GREENER_CHOICE

Product Code. 11514783
Change view
Click to view available options
Quantity:
100 μg
Unit Size:
100µg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
11514783 100 μg 100µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 11514783 Supplier Invitrogen™ Supplier No. MA190186

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Mouse Monoclonal Antibody

This antibody recognizes conjugated and non-conjugated FK-506 with apparent dissociation constant Kd=10^9M.

Tacrolimus is a macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro. Tacrolimus binds to the FKBP-12 protein and forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. [National Center for Biotechnology Information. PubChem Compound Database; CID=445643].
TRUSTED_SUSTAINABILITY

Specifications

Antigen FK506
Applications ELISA
Classification Monoclonal
Clone FK1
Concentration 6 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.09% sodium azide; pH 8.0
Gene Alias C44H69NO12; FK-506; Fujimycin; Tacrolimus
Host Species Mouse
Immunogen Conjugate FK-506-BSA.
Purification Method Euglobulin precipitation, Size-exclusion - Dialysis
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Target Species Chemical
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgM
Target Molecule Chemical
Show More Show Less
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.