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Invitrogen™ FLASH Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA590692

Product Code. 16537941

  • € 520.00 / 100µL

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Description

Description

Immunogen sequence: TVGAFIDLTQ DASSEAKSEG NHPALAVEDL GCGVIQVDED NCKEEKAQVA NRPLKCIVEE TYIDLTTESP SSCEVKKDEL KSEPGSNCDN SELPGTLHNS HKKRRNISDL NHPHKKQRKE TDLTNKEKTK KPTQDSCENT EAHQKKASKK KAPPVTKDPS SLKATPGIKD SSAALATSTS LSAKNVIKKK GEIIILWTRN DDREILLECQ KRGPSFKTFA YLAAKLDKNP NQVSERFQQL MKLFEKSKCR; Positive Samples: U-87MG, K-562; Cellular Location: Cytoplasm, Mitochondrion, Nucleus, PML body.

This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

FLASH
Polyclonal
Unconjugated
CASP8AP2
AA387232; CASP8 associated protein 2; CASP8AP2; CASP8-associated protein 2; caspase 8 associated protein 2; CED-4; D4Ertd659e; FLASH; FLASH homolog RIP25; FLICE associated huge; FLICE-associated huge protein; FLJ11208; human FLASH; KIAA1315; mKIAA1315; RIP25; RP11-63K6.3
Rabbit
Affinity Chromatography
RUO
9994
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Western Blot
0.85 mg/mL
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Q9UKL3
CASP8AP2
Recombinant fusion protein containing a sequence corresponding to amino acids 1733-1982 of human CASP8AP2 (NP_0362471).
100 μL
Primary
Human
Antibody
IgG
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