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Description
The antibody is specific to FLNB. It can recognize isoforms 1,2,3,6, and 7 of FLNB. It has no cross reaction to FLNA and FLNC.
FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus. It also is predomitly expressed in many maligt tissues, such as tumors of the brain, colon and lymph node.
Specifications
Specifications
| Antigen | FLNB |
| Applications | Immunocytochemistry, Immunofluorescence, Western Blot, Immunohistochemistry (Paraffin) |
| Classification | Polyclonal |
| Concentration | 0.21 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | FLNB |
| Gene Accession No. | O75369, Q80X90 |
| Gene Alias | ABP 278, ABP 280 homolog, Actin binding like protein, AOI, Beta filamin, FH1, Filamin 3, Filamin B, Filamin homolog 1, FLN B, FLN1L, FLN3, FLNB, LRS1, SCT, TABP, TAP, Thyroid autoantigen, Truncated ABP |
| Gene Symbols | Flnb |
| Show More |
Product Title
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