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FOLH1 Monoclonal Antibody (OTI5A9), TrueMAB™, OriGene

Product Code. 17541872
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17541872 100 μL 100µL
17561872 30 μL 30µL
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Product Code. 17541872 Supplier Origene Technologies Supplier No. TA504549

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Description

Mouse Monoclonal Antibody

PMSA (FOLH1) is a type II transmembrane glycoprotein belonging to the M28 peptidase family. Three functionally distinct proteins are encoded, including folylpoly-gamma-glutamate carboxypeptidase in the intestine, N-acetylated alpha-linked acidic dipeptidase 1 in the brain, and prostate-specific membrane antigen in the prostate. A mutation in the intestinal form may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. The form expressed in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. The prostate form is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. This gene likely arose from a duplication event of a nearby chromosomal region.

Specifications

Antigen FOLH1
Applications Flow Cytometry, Western Blot
Classification Monoclonal
Clone OTI5A9
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene FOLH1
Gene Accession No. Q04609
Gene Alias FGCP, FOLH, GCP2, GCPII, NAALAD1, NAALAdase, PSM, PSMA, mGCP
Gene Symbols FOLH1
Host Species Mouse
Immunogen Full length human recombit protein of human FOLH1 produced in HEK293T cell.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 2346
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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