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FR4 Rat anti-Mouse, Functional Grade, Clone: eBioTH6, eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-5446-85

Additional Details : Weight : 0.01000kg

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Product Code. 15248647

  • € 425.00 / 500µg


Estimated Shipment
21-07-2020
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Description

Description

Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
Specifications

Specifications

FR4
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
Q9EQF4
Izumo1r
IgG2b, kappa
500 μg
4° C
Primary
64931
Flow Cytometry, Functional Assay, Immunoprecipitation
eBioTH6
Functional Grade
Izumo1r
Liquid
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
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