FR4 Rat anti-Mouse, Functional Grade, Clone: eBioTH6, eBioscience™
Rat Monoclonal Antibody
Brand: Affymetrix eBioscience 16-5446-85
Additional Details : Weight : 0.01000kg
DescriptionStorage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC. FR4 is a heavily glycosylated 35 kD receptor for folic acid and the physiologic circulating form of the vitamin, N5-methyltetrahydrofolate. Natural T regs have high levels of FR4 and together with CD25 can be used to distinguish natural Tregs, effector T cells, memory-like T cells and naive T cells. In vivo studies with eBioTH6 show a decrease in the number of CD4+CD25+ cells and an enhanced tumor response leading to the elimination of advanced stages of tumors.
|PBS with no preservative; pH 7.2|
|Flow Cytometry, Functional Assay, Immunoprecipitation|
For Research Use Only.