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Invitrogen™ FREM1 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA5109737
Description
Immunogen sequence: GSSSSTTSGS FHLERRPLPS SMQLAVIRGD TLRGFDSTDL SQRKLRTRGN GKTVRPSSVY RNGTDIIYNY HGIVSLKLED DSFPTHKRKA KVSIISQPQK TIKVAELPQA DKVESTTDSH FPRQDQLPSF PKNCTLELKG LFHFEEGIQK LYQCNGIAWK AWSPQTKDVE DKSCPAGWHQ HSGYCHILIT EQKGTWNAAA QACREQYLGN LVTVFSRQHM RWLWDIGGRK SFWIGLNDQV HAGHWEWIGG EPVAFTNGRR GPSQRSKLGK SCVLVQRQGK WQTKDCRRAK PHNYVCSRKL.
FREM1 is a member of the FRAS1-related extracellular matrix protein family and is thought to play a role in craniofacial and renal development. FREM1 functions as an extracellular matrix protein that is essential for epidermal adhesion during embryogenesis and may also participate in epidermal differentiation. It is recognized by cells in the embryonic skin and hair follicles through different members of the integrin family. Deficiency in the Fras1/Frem genes gives rise to the bleb phenotype, which is equivalent to the human hereditary disorder Fraser syndrome.
Specifications
| FREM1 | |
| Polyclonal | |
| Unconjugated | |
| FREM1 | |
| BC037594; BNAR; C9orf143; C9orf145; C9orf154; crf11; D430009N09; D630008K06; extracellular matrix protein QBRICK; eye>m02Jus>; eyes2; Fras1 related extracellular matrix 1; Fras1 related extracellular matrix protein 1; FRAS1-related extracellular matrix protein 1; Frem1; heb; MOTA; Protein QBRICK; qbrick; RGD1306981; RP11-265B7.2; TILRR; TRIGNO2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 158326, 298185, 329872 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Western Blot | |
| 1.12 mg/mL | |
| PBS with 50% glycerol and 0.01% thimerosal; pH 7.3 | |
| Q5H8C1, Q684R7 | |
| FREM1 | |
| Recombinant fusion protein containing a sequence corresponding to amino acids 1880-2179 of human FREM1 (NP_659403.4). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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