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  5. Tocris Bioscience™ FTY 720

Tocris Bioscience™ FTY 720
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Product Code. 18792168
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18792168 10 mg 10mg
18761508 50 mg 50mg
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Product Code. 18792168 Supplier Tocris Bioscience™ Supplier No. 6176/10

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134.30 EUR valid until 2026-03-31
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Description

Potent S1P receptor agonist; also immunosuppressant

FTY 720 is an S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∼3 nM for S1P3). Immunosuppressant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.
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Specifications

CAS 162359-56-0
Quantity 10 mg
Target Sphingosine-1-phosphate Receptor
Molecular Formula C19H33NO2.HCl
Formula Weight 343.93g/mol
Product Type Agonist

For Research Use Only

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