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Invitrogen™ FZD4 Polyclonal Antibody
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Product Code. 15527722
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Quantity:
100 μg
Unit Size:
100µg
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15527722 100 μg 100µg
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Product Code. 15527722 Supplier Invitrogen™ Supplier No. PA547228

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Description

Goat Polyclonal Antibody

In direct ELISAs, approximately 5% cross-reactivity with recombinant mouse (rm) Frizzled-8 and less than 2% cross-reactivity with rmFrizzled-3 and rmFrizzled-7 is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

FZD4 is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. Frizzled 4 is widely expressed, particularly in heart, skeletal muscle, ovary, and fetal kidney. Transcripts have also been identified in liver, kidney, pancreas, spleen, and fetal lung, and in smaller amounts in placenta, adult lung, prostate, testis, colon, and fetal brain.
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Specifications

Antigen FZD4
Applications Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene FZD4
Gene Accession No. Q61088
Gene Alias CD344; CD344 antigen; EVR1; FEVR; frizzled 4, seven transmembrane spanning receptor; frizzled class receptor 4; frizzled family receptor 4; frizzled homolog 4; frizzled homolog 4 (Drosophila); frizzled receptor 4; frizzled-4; Fz4; Fz-4; Fzd4; FZD4S; FzE4; GPCR; hFz4; mFz4; MGC34390; rFz4; WNT receptor frizzled-4
Gene Symbols FZD4
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse Frizzled-4 Phe37-Glu180.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14366
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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