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Invitrogen™ GABBR2 Monoclonal Antibody (N81/2), PerCP
Mouse Monoclonal Antibody
Brand: Invitrogen™ MA545535
This item is not returnable.
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Description
1 μg/mL of MA5-45535 was sufficient for detection of GABA(B)R2 in 20 μg of rat brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 105kDa. No cross-reactivity against GABA(B)R1. This antibody was formerly sold as clone S81-2.
The multi-pass membrane protein, GABBR2, belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.
Specifications
| GABBR2 | |
| Monoclonal | |
| 1 mg/mL | |
| 2.48mM MES, 95.64mM phosphate with 0.5M EDTA and no preservative; pH 7.4 | |
| O75899, O88871, Q80T41 | |
| GABBR2 | |
| Fusion protein amino acids 861-912 of rat GABA(B)R2. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG1 |
| Immunohistochemistry, Western Blot, Immunocytochemistry | |
| N81/2 | |
| PerCP | |
| GABBR2 | |
| FLJ36928; G protein-coupled receptor 51; GABA BR; GABA-B R2 receptor; GABA-B receptor 2; GABA-B receptor, R2 subunit; GABABR2; GABA-BR2; GABA-B-R2; Gabbr2; gamma-aminobutyric acid; gamma-aminobutyric acid (GABA) B receptor 2; gamma-aminobutyric acid (GABA) B receptor, 2; gamma-aminobutyric acid B receptor 2; gamma-aminobutyric acid type B receptor subunit 2; gamma-aminobutyric acid type B receptor, subunit 2; gb2; Gm425; Gpr51; GPRC3B; G-protein coupled receptor 51; HG20; HRIHFB2099; MGC119386; MGC119388; MGC119389; ortholog of human G protein-coupled receptor 51 GPR51; RP23-337N2.1 | |
| Mouse | |
| Protein G | |
| RUO | |
| 242425, 83633, 9568 | |
| 4°C | |
| Liquid |
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