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GADD45A Monoclonal Antibody (OTI1C9), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Brand: Origene Technologies TA507370
This item is not returnable.
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Description
GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.Specifications
| GADD45A | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
| P24522 | |
| GADD45A | |
| Full length human recombit protein of human GADD45A produced in HEK293T cell. | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b |
| Western Blot | |
| OTI1C9 | |
| Unconjugated | |
| GADD45A | |
| DDIT1, GADD45 | |
| Mouse | |
| Affinity Chromatography | |
| RUO | |
| 1647 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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