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Invitrogen™ GADD45A Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA576630

Product Code. 15903155

  • € 568.00 / 100µL

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Description

Description

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

GADD45 alpha, beta and gamma are an evolutionarily conserved, homologous family of nuclear proteins that function as stress sensors for cellular physiological and environmental damage. GADD45 proteins are required for the activation of the G2/M checkpoint induced by UV radiation or alkylating agents. GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2-cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, and may serve as core for interaction with other cell cycle regulators.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GADD45A
Polyclonal
Unconjugated
GADD45A
AA545191; DDIT 1; DDIT1; DDIT-1; DNA damage-inducible transcript 1 protein; DNA damage-inducible transcript-1; DNA-damage inducible transcript 1; DNA-damage-inducible transcript 1; GADD45; GADD45A; Gadd45alpha; growth arrest and DNA damage inducible alpha; growth arrest and DNA damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible 45 alpha; growth arrest and DNA-damage-inducible protein GADD45 alpha; growth arrest and DNA-damage-inducible, alpha
Rabbit
Antigen affinity chromatography
RUO
13197, 1647, 25112
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
P24522, P48316, P48317
GADD45A
Recombinant full length Human GADD45A.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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