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Invitrogen™ gamma Actin Polyclonal Antibody
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Product Code. 15335581
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Quantity:
100 μL
Unit Size:
100µL
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15335581 100 μL 100µL
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Product Code. 15335581 Supplier Invitrogen™ Supplier No. PA534667

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Description

Rabbit Polyclonal Antibody

Recommended positive controls: A431, NIH-3T3, JC, BCL-1, PC-12, Rat2. Predicted reactivity: Mouse (100%), Rat (100%), Xenopus laevis (100%), Dog (96%), Chicken (100%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen gamma Actin
Applications Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 10% glycerol and 0.01% thimerosal; pH 7
Gene ACTG1
Gene Accession No. P63259, P63260, P63261
Gene Alias ACT; ACTG; Actg1; actin; actin gamma; actin gamma 1; actin, cytoplasmic 2; Actin, cytoplasmic 2, N-terminally processed; Actin, cytoplasmic type 5; actin, cytoplasmic, type 5; actin, gamma 1; actin, gamma 1 propeptide; actin, gamma, cytoplasmic 1; Actl; AL023024; beta actin; beta-actin FE-3; BRWS2; cytoplasmic 2; cytoplasmic ACTG1; cytoplasmic type 5; cytoskeletal gamma-actin; cytoskeleton actin; deafness, autosomal dominant 20; deafness, autosomal dominant 26; DFNA20; DFNA26; E51; epididymis luminal protein 176; gamma 1 propeptide; gamma actin; gamma-actin; HEL-176; type 5
Gene Symbols ACTG1
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-terminus region of human Actin Gamma 1. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11465, 287876, 71
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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