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Gata-3 Monoclonal Antibody (TWAJ), PE-eFluor™ 610, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 61-9966-41

109.33 EUR valid until 2024-03-29
Use promo code "21615" to get your promotional price.



Additional Details : Weight : 0.23750kg

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Product Code. 15540587

  • € 164.00 / 25 tests
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Description

Description

Description: The monoclonal antibody TWAJ recognizes mouse and human Gata-3, a member of the Gata family of transcription factors. Gata-3 is a T cell-specific transcription factor important for thymic development and Th2 differentiation. Expression during embryonic development is found in the central nervous system, skin, mammary glands and kidney. During development, the expression of Gata-3 is essential as homozygous knock-out of Gata-3 is embryonic lethal. The Gata-3 is also essential for T cell commitment and survival. In the thymus, expression is found mainly on the CD4 single positive cells. During Th2 differentiation, Gata-3 binds to the IL-4 promoter as well as represses the expression of T-bet, thus inhibiting Th1 differentiation. Alternative splice variants have been reported especially in the MCF7 cell line. The TWAJ Human/Mouse Gata-3 antibody will recognize both forms (50 and 45 kDa) of the protein. Staining with the TWAJ Human/Mouse Gata-3 antibody requires the use of the Foxp3/Transcription Factor Staining Buffer Set.(cat 00-5523) Crossreactivity in rhesus monkeys has been published. Applications Reported: This TWAJ antibody has been reported for use in intracellular staining followed by flow cytometric analysis. Applications Tested: This TWAJ antibody has been pre-titrated and tested by intracellular staining and flow cytometric analysis of mouse thymocytes using the Foxp3/Transcription Factor Staining Buffer Set (cat. 00-5523) and protocol.

Gata-3 Monoclonal antibody specifically detects Gata-3 in Human, Mouse, Porcine, Rhesus Monkey samples. It is validated for Flow Cytometry.
Specifications

Specifications

Gata-3
Monoclonal
5 μL/Test
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
P23771, P23772
GATA3
Affinity chromatography
RUO
14462, 2625, 713840, 733631
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
TWAJ
PE-eFluor 610
GATA3
EGK_19445; GATA binding factor-3; GATA binding protein 3; GATA binding protein-3; GATA3; Gata-3; GATA-binding factor 3; GATA-binding protein 3; HDR; HDRS; jal; MGC2346; MGC5199; MGC5445; Trans-acting T-cell-specific transcription factor GATA-3; Transacting T-cell-specific transcription factor GATA-3
Rat
25 Tests
Primary
Human, Mouse, Porcine, Rhesus Monkey
Antibody
IgG2b κ
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