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Invitrogen™ GBL Polyclonal Antibody
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Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA520127

Product Code. 12858362

  • € 566.00 / 100µg

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Description

Description

A suggested positive control is human brain tissue lysate. PA5-20127 can be used with blocking peptide PEP-0245.

G-protein beta subunit like (GBL protein) is a novel member of WD-40 protein family. It is a highly conserved cytosolic protein consisting of seven WD-40 repeating motifs. LST8 is a functional component of mTOR signaling complex (TORC1) and positively up-regulates the mTOR pathway. It interacts with the kinase domain of mTOR and stabilizes its interaction with raptor. LST8 participates in regulating cell growth and also in nutrient and growth factor-mediated mTOR signaling to S6K1. Reports suggest up-regulated expression of LST8 due to insulin indicating a possible role of LST8 in intracellular events related to insulin-receptor activation including insulin-stimulated glucose transport and glycogen synthesis. Northern Blot analysis detected a ubiquitous expression of LST8 with highest expression in brain and testis.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GBL
Polyclonal
Unconjugated
MLST8
0610033N12Rik; AA409454; AI505104; AI851821; G beta-like protein; G protein beta subunit-like; Gable; GbetaL; GBL; GBL protein; Lst8; Mammalian lethal with SEC13 protein 8; mLST8; mLST8 / mLST8; MTOR associated protein, LST8 homolog; MTOR associated protein, LST8 homolog (S. cerevisiae); POP3; protein GbetaL; Target of rapamycin complex subunit LST8; TORC subunit gable; TORC subunit LST8; TORC subunit WAT1; transducin (beta)-like 4; WAT1
Rabbit
Antigen Affinity Chromatography
RUO
56716, 64223, 64226
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Liquid
Immunohistochemistry, Western Blot, Immunocytochemistry
1 mg/mL
PBS with 0.02% sodium azide
Q9BVC4, Q9DCJ1, Q9Z2K5
MLST8
A 14 amino acid peptide from near the carboxy terminus of human GbL.
100 μg
Primary
Human, Mouse, Rat
Antibody
IgG
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