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Invitrogen™ GCN2 Recombinant Rabbit Monoclonal Antibody (1G2Z4)
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA535353
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Description
Immunogen sequence: MAGGRGAPGR GRDEPPESYP QRQDHELQAL EAIYGADFQD LRPDACGPVK EPPEINLVLY PQGLTGEEVY VKVDLRVKCP PTYPDVVPEI ELKNAKGLSN ESVNLLKSRL EELAKKHCGE VMIFELAYHV QSFLSEHNKP PPKSFHEEML ERRAQEEQQR LLEAKRKEEQ EQREILHEIQ RRKEEIKEEK KRKEMAKQER LEIASLSNQD HTSKKDPGGH RTAAILHGGS PDFVGNGKHR ANSSGRSRRE RQYSVCNSED SPGSCEILYF NMGSPDQLMV HKGKCIGSDE QLGKLVYNAL.
EIF2AK4 (GCN2) is a metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor-2 in response to low amino acid availability. It plays a role as an activator of the integrated stress response required for adapatation to amino acid starvation. Mutations in the gene lead to pulmonary vennocclusive disease 2.
Specifications
| GCN2 | |
| Recombinant Monoclonal | |
| 1.0 mg/mL | |
| PBS with 50% glycerol, 0.05% BSA and 0.05% ProClin 300; pH 7.3 | |
| D4A7V9, Q9P2K8, Q9QZ05 | |
| EIF2AK4 | |
| Recombinant protein (or fragment). | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
| ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry | |
| 1G2Z4 | |
| Unconjugated | |
| EIF2AK4 | |
| 2610011M03; EIF2AK4; eIF-2-alpha kinase GCN2; eukaryotic translation initiation factor 2 alpha kinase 4; eukaryotic translation initiation factor 2-alpha kinase 4; Gcn2; GCN2 eIF2alpha kinase; GCN2-like protein; general control nonderepressible 2; Kiaa1338; mGCN2; PVOD2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 114859, 27103, 440275 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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