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GDC-0339, MedChemExpress

Product Code. 16427238
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Product Code. 16427238 Supplier Medchem Express Supplier No. HY16976

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Description

MedChemExpress GDC-0339 is a potent, orally bioavailable and well tolerated pan-Pim kinase inhibitor, with Kis of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. GDC-0339 is discovered as a potential treatment of multiple myeloma.

GDC-0339 is a potent, orally bioavailable and well tolerated pan-Pim kinase inhibitor, with Kis of 0.03 nM, 0.1 nM and 0.02 nM for Pim1, Pim2 and Pim3, respectively. GDC-0339 is discovered as a potential treatment of multiple myeloma.

Specifications

Chemical Name or Material GDC-0339
CAS 1428569-85-0
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C20H22F3N7OS
Quantity 10 mg
Solubility Information DMSO : ≥ 52 mg/mL (111.71 mM)
SMILES FC1=CC=CC(F)=C1C2=NC(C(NC3=C(N4CC[C@@H](F)[C@H](N)CC4)N(C)N=C3)=O)=C(N)S2
Molecular Weight (g/mol) 465.5
Formula Weight 465.5
Percent Purity 99.07%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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