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Invitrogen™ GDF15 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA517065
This item is not returnable.
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Description
It is not recommended to aliquot this antibody.
GDF-15 belongs to the TGF-beta cytokine family, whose members play an important role during prenatal development and postnatal growth, and the remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in the placenta and, to a much lesser extent, in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest GDF-15's involvement in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers.
Specifications
| GDF15 | |
| Polyclonal | |
| 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5 | |
| Q99988 | |
| Gdf15 | |
| Synthetic peptide corresponding to residues near the carboxyl terminus of human Mic-1. | |
| 100 μL | |
| Primary | |
| Human, Monkey | |
| Antibody | |
| IgG |
| Western Blot | |
| Unconjugated | |
| Gdf15 | |
| Gdf15; GDF-15; growth differentiation factor 15; growth/differentiation factor 15; macrophage inhibiting cytokine-1; macrophage inhibitory cytokine 1; MIC1; MIC-1; NAG1; NAG-1; NRG-1; NSAID (nonsteroidal anti-inflammatory drug)-activated protein 1; NSAID-activated gene 1 protein; NSAID-regulated gene 1 protein; PDF; PLAB; Placental bone morphogenetic protein; placental TGF-beta; Prostate differentiation factor; PTGFB; PTGF-beta; SBF | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 9518 | |
| -20°C | |
| Liquid |
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