missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Gemtuzumab Chimeric Recombinant Rabbit Monoclonal Antibody (hP67.6 (Gemtuzumab))
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA547867
This item is not returnable.
View return policy
Description
Specificity: Recognises human CD33.
Gemtuzumab ozogamicin is a recombinant humanized IgG4 kappa antibody which is conjugated with calicheamicin derivative, a cytotoxic antitumor antibiotic isolated from fermentation of Micromonospora echinospora ssp. calichensis. Gemtuzumab ozogamicin has approximately 50% of the antibody loaded with 4-6 moles calicheamicin per mole of antibodyLabel. The antibody is specifically directed against the CD33 antigen present on leukemic myeloblasts in most patients with acute myeloid leukemia (AML). By binding to the CD33 antigen on tumors, the cytotoxic agent blocks the growth of cancerous cells and causes cell death.
Specifications
| Gemtuzumab Chimeric | |
| Recombinant Monoclonal | |
| 1 mg/mL | |
| PBS with 0.02% ProClin 300 | |
| Rabbit | |
| Protein A | |
| RUO | |
| Human | |
| Antibody | |
| IgG κ |
| Flow Cytometry, Immunocytochemistry | |
| hP67.6 (Gemtuzumab) | |
| Unconjugated | |
| CDP-771; CMA-676 (ADC); gemtuzumab ozogamicin; hP67.6; hP67.6-calicheamicin (ADC); WAY-CMA-676 | |
| Gemtuzumab was generated by huminization of the murine P67.6 clone, raised against CD33-transfected FMY9S5 cells of human origin. | |
| 200 μg | |
| Primary | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
Product Content Correction
Your input is important to us. Please complete this form to provide feedback related to the content on this product.
Product Title
Spot an opportunity for improvement?Share a Content Correction