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Tocris Bioscience™ Genistein
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Product Code. 18712804
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50 mg
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18712804 50 mg 50mg
18702704 10 mg 10mg
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Product Code. 18712804 Supplier Tocris Bioscience™ Supplier No. 1110/50

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237.20 EUR valid until 2026-03-31
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Description

EGFR kinase inhibitor. Also estrogen and PPARγ ligand

Genistein is a phytoestrogen with a wide range of biological actions. Genistein inhibits protein tyrosine kinases including epidermal growth factor receptor kinase, binds to PPARγ and estrogen receptors and acts as an agonist at GPER. Genistein inhibits aggregation and fibrilization of Aβ42 and amylin37 (hiAPP). In Huntington's disease fibroblast cells, Genistein reduces intracellular mutant huntingtin (mHTT) aggregates and induces degradation of mHTT; in a cellular model of Huntington's disease, Genistein corrects the mutant phenotype through stimulation of autophagy.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 446-72-0
Molecular Formula C15H10O5

Specifications

Quantity 50 mg
Formula Weight 270.24
Purity >98%
Molecular Weight (g/mol) 270.24
Chemical Name or Material Genistein
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