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Invitrogen™ GFM2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA585482
This item is not returnable.
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Description
Keep as concentrated solution. Predicted reactivity: Mouse (88%), Rat (87%), Rhesus Monkey (98%), Bovine (91%). Positive Control: 293T, A431, HeLa, HepG2, Neuro 2A, C8D30. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
GFM2 is involved in mitochondrial translation, which is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. In Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. This gene encodes one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in at least three transcript variants encoding distinct isoforms.
Specifications
| GFM2 | |
| Polyclonal | |
| Unconjugated | |
| Gfm2 | |
| 6530419G12Rik; A930009M04Rik; EFG2; EF-G2mt; EF-G2mt {ECO:0000255; Elongation factor G 2, mitochondrial; elongation factor G 2, mitochondrial {ECO:0000255; Elongation factor G2; G elongation factor; G elongation factor mitochondrial 2; G elongation factor, mitochondrial 2; GFM2; HAMAP-Rule:MF_03059}; hEFG2; mEF-G 2; mEF-G 2 {ECO:0000255; mitochondrial elongation factor G2; mitochondrial ribosome recycling factor 2; MRRF2; MST027; MSTP027; RGD1309854; ribosome-releasing factor 2, mitochondrial; ribosome-releasing factor 2, mitochondrial {ECO:0000255; RRF2; RRF2mt; RRF2mt {ECO:0000255 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 320806, 84340 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 20% glycerol and 0.025% ProClin 300; pH 7 | |
| Q8R2Q4, Q969S9 | |
| Gfm2 | |
| Recombinant protein encompassing a sequence within the center region of human GFM2. The exact sequence is proprietary. | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
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