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Invitrogen™ GIPR Chimeric Recombinant Mouse Monoclonal Antibody (Gipg013)

Description
The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.
GIPR encodes a G-protein coupled receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking this gene exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in this gene thus may contribute to the pathogenesis of diabetes.
Specifications
Specifications
| Antigen | GIPR Chimeric |
| Applications | ELISA, Inhibition Assays, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | Gipg013 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.02% ProClin 300 |
| Gene | GIPR |
| Gene Accession No. | P43219, P48546, Q0P543 |
| Gene Alias | gastric inhibitory peptide receptor; gastric inhibitory polypeptide receptor; GIP receptor; Gippr; Gipr; GIP-R; Glucose-dependent insulinotropic polypeptide receptor; Gm1081; Gm160; PGQTL2; RATGIPPR |
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Product Title
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