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GLE1 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 26466-1-AP-20UL
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Description
The proper expression of gene products in eukaryotic cells relies on efficient transport of mRNA molecules out of the nucleus. Gle1 is an essential mRNA export factor in both human and yeast cells. It associates with the nuclear pore complex (NPC) through hCG1 and NUP155 in mammalian cells and in conjunction with inositol hexakisphosphate (IP6), stimulates Dbp5, a member of the DEAD-box helicase family, triggering mRNP remodeling and facilitating RNA export from the nucleus. Recent evidence suggests that mutations in Gle1 causing defects in mRNA export can result in human disease. At least three isoforms of Gle1 are known to exist.Specifications
| GLE1 | |
| Polyclonal | |
| Unconjugated | |
| GLE1 | |
| GLE1, GLE1 like protein, GLE1L, hGLE1, LCCS, LCCS1, Nucleoporin GLE1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 2733 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Western Blot, Immunocytochemistry | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| Q53GS7 | |
| GLE1 | |
| GLE1 Fusion Protein Ag24208 | |
| 20 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
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