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GLI2 Mouse anti-Human, Clone: OTI1G2, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Brand:  Origene Technologies CF804599

Encompass_Preferred

Product Code. 17648061

  • € 726.00 / 100µg

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This item is not returnable. View return policy

Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes- Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B.
Specifications

Specifications

GLI2
Monoclonal
Unconjugated
GLI2
CJS, HPE9, PHS2, THP1, THP2
Mouse
Affinity Chromatography
RUO
2736
-20° C, Avoid Freeze/Thaw Cycles
Lyophilized
Western Blot
OTI1G2
PBS with 8% trehalose and no preservative; pH 7.3
P10070
GLI2
Human recombit protein fragment corresponding to amino acids 729-1123 of human GLI2 produced in E.coli.
100 μg
Primary
Human
Antibody
IgG1
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