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Invitrogen™ GLRX Recombinant Rabbit Monoclonal Antibody (3N3Y7)
Description
Immunogen Sequence: QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ.
Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxidoreductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12-kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress.
Specifications
Specifications
| Antigen | GLRX |
| Applications | ELISA, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 3N3Y7 |
| Concentration | 1.14 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.05% BSA and 0.05% ProClin 300; pH 7.3 |
| Gene | GLRX |
| Gene Accession No. | P35754, Q9ESH6, Q9QUH0 |
| Gene Alias | C86710; D13Wsu156e; GLRX; Glrx1; GLRXL; glutaredoxin; glutaredoxin (thioltransferase); glutaredoxin 1; glutaredoxin 1 (thioltransferase); Glutaredoxin1; glutaredoxin-1; Grx; Grx 1; Grx1; MGC117; MGC117407; thiol disulfide oxidoreductase; thioltransferase; Thioltransferase 1; thioltransferase; TTase; Thioltransferase1; Thioltransferase-1; TTase; TTase 1; TTase1; TTase-1; TTF; Unknown (protein for MGC:133817) |
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