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Invitrogen™ GLT-1 Recombinant Rabbit Monoclonal Antibody (9H9L17)

Product Code. 15825753
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Quantity:
100 μg
Unit Size:
100µg
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15825753 100 μg 100µg
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Product Code. 15825753 Supplier Invitrogen™ Supplier No. 701988

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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Rabbit and Sheep Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Excitatory amino acid transporter 2 (EAAT2) is a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis (ALS.) Alternatively spliced transcript variants of this gene have been identified.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GLT-1
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 9H9L17
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene SLC1A2
Gene Accession No. P31596, P43004, P43006
Gene Alias 1700091C19Rik; 2900019G14Rik; AI159670; Eaat2; EAAT2 variant mEAAT2/5UT5; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; Glt; GLT1; GLT-1; GLT1a; GLT1b; GLT1c; glutamate transporter 1c; glutamate/aspartate transporter II; GLUT-R; HBGT; high affinity glucose transporter; MGLT1; OTTHUMP00000165209; OTTHUMP00000165210; SLC1A2; Sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; solute carrier family 1 member 2; solute carrier family 1, member 2
Gene Symbols SLC1A2
Host Species Rabbit
Immunogen Peptides corresponding to Human SLC1A2 (aa 5-20, 148-166).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20511, 29482, 6506
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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