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Invitrogen™ Glucagon Receptor Recombinant Rabbit Monoclonal Antibody (21H1L9)

Product Code. 15895763
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Quantity:
100 μg
Unit Size:
100µg
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15895763 100 μg 100µg
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Product Code. 15895763 Supplier Invitrogen™ Supplier No. 702602

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Description

Rabbit Recombinant Monoclonal Antibody

This antibody is predicted to react with Monkey, Horse, Bovine, Dog Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Glucagon Receptor
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone 21H1L9
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene GCGR
Gene Accession No. P30082, P47871
Gene Alias GCGR; GGR; GL-R; Glucagon receptor; glucagon receptor perhaps same as Niddm3; GR
Gene Symbols GCGR
Host Species Rabbit
Immunogen Peptide corresponding to human Glucagon Receptor (aa198-aa211).
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 24953, 2642
Target Species Human, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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