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Invitrogen™ GluR4 Recombinant Rabbit Monoclonal Antibody (4M5D0)

Description
Immunogen sequence: SGSKDKTSAL SLSNVAGVFY ILVGGLGLAM LVALIEFCYK SRAEAKRMKL TFSEAIRNKA RLSITGSVGE NGRVLTPDCP KAVHTGTAIR QSSGLAVIAS DLP.
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7. The kainate/AMPA receptors are primarily responsible for the fast excitatory neuro-transmission by glutamate, whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions.
Specifications
Specifications
| Antigen | GluR4 |
| Applications | ELISA, Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | 4M5D0 |
| Concentration | 0.84 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | Gria4 |
| Gene Accession No. | P19493, Q9Z2W8 |
| Gene Alias | AMPA-selective glutamate receptor 4; GluA4; GLUR4; Glur-4; GLUR4C; Gluralpha4; GLURD; GluR-D; glutamate ionotropic receptor AMPA type subunit 4; glutamate receptor; glutamate receptor 4; glutamate receptor channel alpha 4; glutamate receptor ionotropic, AMPA 4; glutamate receptor, ionotrophic, AMPA 4; glutamate receptor, ionotropic, AMPA 4; glutamate receptor, ionotropic, AMPA4 (alpha 4); Gria4; spike wave 1; spkw1 |
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