Invitrogen™ Glutathione Monoclonal Antibody (D8)

Beskrivelse

MA1-7620 detects Glutathione from all organism samples. MA1-7620 has been successfully used in ELISA, WB and IP procedures. The MA1-7620 immunogen is a Glutathione protein. Store at 4°C short term. For long term storage, store at -80°C.

Glutathione is a tripeptide comprised of three amino acids (cysteine, glutamic acid, and glycine) present in most mammalian tissue. Glutathione acts as an antioxidant, a free radical scavenger and a detoxifying agent. Glutathione is also important as a cofactor for the enzyme glutathione peroxidase, in the uptake of amino acids, and in the synthesis of leukotrienes. As a substrate for glutathione S-transferase, this agent reacts with a number of harmful chemical species, such as halides, epoxides and free radicals, to form harmless inactive products. In erythrocytes, these reactions prevent oxidative damage through the reduction of methemoglobin and peroxides. Glutathione is also involved in the formation and maintenance of disulfide bonds in proteins and in the transport of amino acids across cell membranes.