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Invitrogen™ Glypican 3 Monoclonal Antibody (CL12711)
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Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA546531

Product Code. 17868965

  • € 433.00 / 100µL

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Description

Description

Highest antigen sequence indentity to the following orthologs: Mouse - 100%, Rat - 100%.

GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Glypican 3
Monoclonal
0.97 mg/mL
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
P51654
GPC3
Synthetic Peptide.
100 μL
Primary
Human
Antibody
IgG2b
Immunohistochemistry (Paraffin)
CL12711
Unconjugated
GPC3
defective in Simpson-Golabi-Behmel overgrowth syndrome; DGSX; glypican 3; glypican proteoglycan 3; glypican-3; Glypican-3 alpha subunit; Glypican-3 beta subunit; Gpc3; GTR22; GTR2-2; heparan sulphate proteoglycan; intestinal protein OCI-5; MXR7; OCI5; OCI-5; proteoglycan GPC3; SDYS; secreted glypican-3; SGB; SGBS; SGBS1
Mouse
Protein A
RUO
2719
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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