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Invitrogen™ GNA13 Recombinant Rabbit Monoclonal Antibody (JE63-76)
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Rabbit Recombinant Monoclonal Antibody

Brand:  Invitrogen™ MA544800

Product Code. 17846772

  • € 480.00 / 100µL

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Description

Description

GNA13 Recombinant Monoclonal Antibody for Western Blot, IHC (P)

Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:15240885, PubMed:16787920, PubMed:16705036, PubMed:27084452). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:15240885, PubMed:12515866). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1). Promotes tumor cell invasion and metastasis by activating RhoA/ROCK signaling pathway (PubMed:16787920, PubMed:16705036, PubMed:27084452). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (PubMed:11976333). [UniProt].
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GNA13
Recombinant Monoclonal
1 mg/mL
TBS with 0.05% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
P27601, Q14344, Q6Q7Y5
GNA13
Recombinant protein within human GNA13 aa 278-377/377.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Immunohistochemistry (Paraffin), Western Blot
JE63-76
Unconjugated
GNA13
AU024132; AU043124; G alpha 13; G alpha-13; G protein subunit alpha 13; G13; Galpha 13; Galpha13; Gna13; Gna-13; G-protein subunit alpha-13; guanine nucleotide binding protein (G protein), alpha 13; guanine nucleotide binding protein, alpha 13; guanine nucleotide-binding protein subunit alpha-13
Rabbit
Protein A
RUO
10672, 14674, 303634
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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