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Description
Guanine nucleotide-binding proteins are a family of heterotrimeric proteins that couple cell surface, 7-transmembrane domain receptors to intracellular signaling pathways. Receptor activation catalyzes the exchange of GTP for GDP bound to the inactive G protein alpha subunit resulting in a conformational change and dissociation of the complex. The G protein alpha and beta-gamma subunits are capable of regulating various cellular effectors. Activation is terminated by a GTPase intrinsic to the G-alpha subunit. G-alpha-q is the alpha subunit of one of the heterotrimeric GTP-binding proteins that mediates stimulation of phospholipase C-beta (MIM 600230).
Specifications
Specifications
| Antigen | GNAQ |
| Applications | Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.13 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | GNAQ |
| Gene Accession No. | P21279, P50148 |
| Gene Alias | G ALPHA q, GAQ, GNAQ |
| Gene Symbols | GNAQ |
| Show More |
Product Title
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