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Description
Immunogen sequence: TPMFDPSLLK EVDWSQNTAT FSPAISPTHP GEGLVLRPLC TADLNRGFFK VLGQLTETGV VSPEQFMKSF EHMKKSGDYY VTVVEDVTLG QIVATATLII EHKFIHSCAK RGRVEDVVVS DECRGKQLGK LLLSTLTLLS KKLNCYKITL ECLPQNVGFY KKFGYTVSEE NYMCRR Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.
Glucosamine-6 phosphate-N-acetyl Transferase (GNPNAT1) is a key enzyme in the hexosamine biosynthetic pathway. It converts D-glucosamine 6-phosphate to N-acetyl-D-glucosamine 6-phosphate, the acetylation step allowing carbon and nitrogen enter into the hexosamine biosynthetic pathway. Recently inhibition of GNPNAT1 has been reported to promote proliferation and aggressiveness of castration-resistant prostate cancer. (27194471).
Specifications
Specifications
| Antigen | GNPNAT1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | GNPNAT1 |
| Gene Accession No. | Q96EK6, Q9JK38 |
| Gene Alias | AU017428; AU040593; EMeg32; Glucosamine 6-phosphate N-acetyltransferase; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase 1; glucosamine-phosphate N-acetyltransferase 1; glucosamine-6-phosphate acetyltransferase; glucosamine-phosphate N-acetyltransferase; GNA1; GNPNAT; GNPNAT1; Gpnat1; Gsnpat; Phosphoglucosamine acetylase; phosphoglucosamine transacetylase; Protein EMeg32; RGD1563144 |
| Gene Symbols | GNPNAT1 |
| Show More |
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