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ACO1, Goat, Polyclonal Antibody, Abnova™
Goat polyclonal antibody raised against synthetic peptide of ACO1.
Brand: Abnova PAB18708.100ug
This item is not returnable.
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Description
Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes. [provided by RefSeq]
Sequence: C-QVDFNRRADSLQKNQSpecifications
| ACO1 | |
| Polyclonal | |
| Unconjugated | |
| ELISA (1:8000) Western Blot (0.1-0.3 ug/mL) The optimal working dilution should be determined by the end user. | |
| ACO1 | |
| ACONS/IREB1/IREBP/IREBP1/IRP1 | |
| Goat | |
| Antigen affinity purification | |
| RUO | |
| 48 | |
| Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
| ELISA, Western Blot | |
| 0.5 mg/mL | |
| Goat polyclonal antibody raised against synthetic peptide of ACO1. | |
| In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA) | |
| NP_002188.1 | |
| ACO1 | |
| A synthetic peptide corresponding to amino acids at internal region of human ACO1. | |
| 100 μg | |
| Primary | |
| Human | |
| Liquid |
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