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ACVR1, Goat, Polyclonal Antibody, Abnova™

Product Code. 16010498
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Quantity:
100 μg
Unit Size:
100µg
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16010498 100 μg 100µg
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Product Code. 16010498 Supplier Abnova Supplier No. PAB7414.100ug

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Description

Goat polyclonal antibody raised against synthetic peptide of ACVR1.

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive. [provided by RefSeq

Sequence: C-RKFKRRNQERLNPRD

Specifications

Antigen ACVR1
Applications ELISA, Immunohistochemistry (PFA fixed), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Description Goat polyclonal antibody raised against synthetic peptide of ACVR1.
Dilution ELISA (1:128000) Western blot (0.3-1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL) The optimal working dilution should be determined by the end user.
Formulation In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Gene ACVR1
Gene Accession No. NP_001096.1
Gene Alias ACTRI/ACVR1A/ACVRLK2/ALK2/FOP/SKR1/TSRI
Gene Symbols ACVR1
Host Species Goat
Immunogen A synthetic peptide corresponding to human ACVR1.
Purification Method Antigen affinity purification
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 90
Target Species Human
Content And Storage Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
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